The Cor de Noies was set up in the year 2000 by Lluís Vilamajó, who was its director for the first seven years. Since then Buia Reixach i Feixes has been the director and Josep Surinyac the pianist. It is made up of young people aged from sixteen to twenty-five, most of whom started out in the Orfeó Català's children's choirs.

It has worked with the conductors X. Sans, J. Busto, P. Ll. Biosca, X. Puig and X. Pastrana (Cor Simfònic Femení de Catalunya), M. Minkowski (The Nutcracker, Palau 100), Diego Martin-Etxebarria (The Planets, Holst), E. van Tiel (Harry Potter and the Philosopher's Stone), M. Valdivieso (“La Venècia de Vivaldi” and Mahler's Third Symphony) and Norman Huynh (Harry Potter and the Chamber of Secrets); and with the organist David Malet, as well as the Orquestra Camera Musicae, Vespres d’Arnadí, Les Musiciens du Louvre, Orquestra Simfònica del Vallès and Jove Orquestra Nacional de Catalunya.

It has performed all in Spain, Germany, France and Slovenia. In 2005 it won second prize in the girls' choir section of the Festival Internacional de Cantonigròs. It has recorded the CDs Viatjant... (2004) and Germinans (2011). In the 2016-17 season it took part in the Heimat Project, together with the women's choir Mädchenchor Hannover, conducted by Simon Halsey.

Highlights among its recent projects include its performance of Considering Matthew Shepard by Craig Hella Johnson with the Orfeó Català, the Cor de Cambra del Palau and the choirs of the Orfeó Català choir school, conducted by Simon Halsey; participation in the Festival de Música Antiga dels Pirineus with the programme “Ressons de l’antiga Europa”, and a performance of the opera The Monster in the Maze by Jonathan Dove, alongside all the Orfeó Català choirs and the Jove Orquestra Nacional de Catalunya, conducted by Simon Halsey, at the Festival Grec 2018.

The Cor de Noies forms part of the Escola Coral or choir school of the Orfeó Català, which is sponsored by the Banco Santander foundation.